Cholesterol became a popular health topic in the early 2000s, with many campaigns emphasizing its importance. While discussions around it have quieted down in recent years, its impact on health remains significant. In 2021, around 59% of people in the UK had high cholesterol. The condition was most common among individuals aged 45 to 64 (72%). Among younger adults (16 to 33), men (53%) were more likely than women (46%) to have elevated cholesterol levels.
A new study now suggests that lowering “bad” cholesterol, known as low-density lipoprotein (LDL-C), may reduce the risk of dementia. Researchers found that people with lower LDL-C levels were 26% less likely to develop dementia and Alzheimer’s disease. The study also examined the effects of statins—medications designed to lower cholesterol—and found they provide additional protection against these conditions.
What Are Statins?
Statins are medications that help reduce LDL cholesterol levels in the bloodstream. They work by limiting the liver’s ability to produce cholesterol, thereby decreasing overall levels. Doctors typically prescribe statins to individuals with high cholesterol, as excess LDL-C can lead to hardened and narrowed arteries, increasing the risk of cardiovascular diseases such as heart attacks and strokes, according to Yahoo Life.
Statins are available in tablet form and are usually taken once a day. The dosage varies based on individual medical needs and may be adjusted over time as prescribed by a healthcare provider. In most cases, once a person starts taking statins, they continue using them for life.
Possible Side Effects of Statins
While statins are generally safe, some individuals may experience side effects, including:
Headaches
Dizziness
Nausea
Digestive issues (such as diarrhea, constipation, or indigestion)
Muscle pain
Sleep disturbances
Fatigue or weakness
Low blood platelet count
Rare but serious side effects include:
Muscle damage (especially when taken with certain other medications)
Nerve issues, such as tingling or loss of sensation
Tendon problems
Hair loss
Memory issues
Skin irritation
Decreased sex drive or erectile dysfunction
Vomiting
Liver damage
Additional Benefits of Statins
Beyond lowering cholesterol, statins may offer other health benefits:
Lower Risk of Alzheimer’s Disease
In addition to the recent study linking low LDL-C levels to a reduced risk of dementia, a 2016 study found that men who took statins regularly for two years had a 12% lower risk of developing Alzheimer’s disease. This study analyzed data from 400,000 Medicare patients, further supporting the potential neurological benefits of these medications, as per Yahoo Life.
Potential Cancer Risk Reduction
Researchers have explored whether statins can lower the risk of certain cancers. However, studies have produced mixed results, and there is no definitive conclusion yet. Further research is needed to determine their effectiveness in cancer prevention.
Anti-Inflammatory Properties
Statins have been found to reduce inflammation, which plays a role in the development of heart disease. By lowering inflammation levels, statins may help prevent atherosclerosis (the hardening of arteries) and reduce the risk of cardiovascular complications.
Supporting the Immune System
A 2019 study published in Nature Communications discovered a connection between statins and immune system regulation. The research suggested that statins could influence how immune cells respond to infections and diseases. According to lead researcher Professor Andrew Cope, this might explain why statin users tend to recover better from influenza and have improved outcomes for some types of cancer, as per Yahoo Life.
Final Thoughts
Statins play a crucial role in managing cholesterol and reducing the risk of serious health conditions like heart disease and dementia. While they come with potential side effects, their benefits often outweigh the risks for individuals with high cholesterol. If you are considering statins or have concerns about cholesterol, it’s always best to consult a healthcare professional to determine the most suitable treatment plan for you.